Can a 64-bit computer (x86) run a 16-bit OS natively, without emulation?

If you were to build a modern x86 computer with completely modern parts, could you load MS-DOS 6.11 and Windows 3.11 onto it without any emulation or even with FreeDOS? I recently saw a video of it being done with Windows 95, a 32-bit OS, but can it be done with a 16-bit OS like Windows 3.1 or even lower?